I.V. Administration Sets with in-line filters.
Publishing Details Pete Phillips Deputy Director SMTL Revision: $Revision: 1.6 $ Date: $Date: 1998/02/12 12:46:24 $ |
Table of Contents Introduction Sets on the All Wales contract. Non-contract, Non-Dedicated sets Dedicated sets Further Information |
Introduction
Recent events in the UK have highlighted the fact that under some circumstances, users injecting drugs and additives into IV fluid bags sometimes scrape the needle along the plastic tube, resulting in strips of plastic (frequently spirals of plastic) peeling off the walls and ending up in the IV fluid. St Mary's Pharmaceutical Unit (Penarth, South Wales) have stated that they believe that the 200 µ filters in blood sets will contain the particles in question.
This problem can usually be avoided by ensuring that the needle penetrates the injection port at 90° and not at an angle.
However, the IV fluid provider to the Welsh NHS contract (Maco Pharma) informed pharmacy departments (in January 1998) that "as a precautionary measure and until further notice, all Maco Pharma bags must be administered using a giving set with an incorporated filter."
This document was written in response to that letter to provide advice to pharmacists on which IV sets on the UK market had filters and which did not.
On April 7th 1998, Maco Pharma wrote another letter stating that "we are now in a position to advise you that due to modified manufacture of our injection port, it is no longer necessary to filter our products."
However, Maco Pharma have made no changes to the design of the product, but have increased the level of quality control in the manufacturing process to ensure that there are no particulates in the additive port. This does not prevent a user inadvertently scraping the sides of the port and generating the particles referred to above.
We believe that the Maco Pharma advice is incorrectly worded. We do not believe that Maco Pharma solutions require extra precautions, compared to other IV solutions. However, particles may also be produced whenever membranes are pierced on entry into bags, vials, injection ports and whenever glass ampoules are opened. Therefore SMTL and St Marys Pharmaceutical Unit advise that sets conforming to the British Standard 2463 Part 2 be used in all circumstances except where a specific reason has been given, no matter what IV solution bag is being used.
Sets conforming to British Standard BS 2463, Part 2, are required to incorporate a filter. If the set is a solution set, the filter must be a 40µ filter or smaller, and for blood sets, the filters may be of any size providing they filter blood to the same extent as a reference 200µ filter.
This document lists most of the sets in use in the UK (including those on the All Wales contract), and includes information on whether they have a filter, and the pore size of that filter.
Caution should be exercised in the use of filters which have a pore diameter of less than 10 microns due to the frequent use of emulsions and liposomal preparations which may not pass through such filters. Check the compatibility of any such fluids with the filter in your administration set.
Also, note that whilst solution sets conforming to the British Standard have filter pore sizes of 40µ or less, these are not bacterial retention filters. Pore sizes of around 0.22µ are required for bacterial retention.
Sets on the All Wales contract.
Baxter
The following table shows the Baxter sets on contract in Wales, whether they have a filter, and the pore size of the filter.
Table 1: Baxter All Wales Contract Sets
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Baxter | Solution set, burette microdrip. | C9602 (previously C0163) | 15µ |
Baxter | Simple solution set. | C9608 | 15µ |
Baxter | Blood burette set. | C9601, previously C0142 | 200µ |
Baxter | Blood set with pump chamber. | C2071 | 200µ |
Baxter | Blood set with pump chamber. | C2090A/C2071A | 200µ |
Baxter | Primary solution set with non-reflux valve. | C9605 | 15µ |
Baxter | Primary solution set with reflux valve. | C9603 | 15µ |
Baxter | Secondary solution set. | C0429 | 180µ |
Codan
Table 2: Codan All Wales contract sets.
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Codan | SMS System set. | 76.3700 | 15µ |
Codan | SMS Primary solution set. | 37.3143 | 15µ |
Codan | SMS Secondary set. | 37.3144 | 15µ |
Codan | Standard solution set. | 37.3137 | 15µ |
Non-contract, Non-Dedicated sets
Avon
Avon sets are distributed by Sims in the UK.
Table 3: Avon non-dedicated sets.
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Avon | Solution set. | A26 | 15µ |
Avon | Primary solution set. | A21 | 15µ |
Avon | Secondary solution set. | A22 | 15µ |
Avon | Vented solution set. | A220 | 15µ |
Avon | Solution set (OBSOLETE). | A226 | 15µ |
Avon | Microdrip (60 drops/ml) solution set. | A263 | 15µ |
Avon | Blood set. | A100 | 200µ |
Avon | Blood set. | A120 | 200µ |
Avon | Blood set - Y-type, 3mm. | A13 | 200µ |
Avon | Blood set. | A122 | 200µ |
Avon | Burette (150ml) solution set. | A200A | 15µ |
Avon | Burette (150ml) blood set. | A201 | 200µ |
Avon | Burette (150ml) solution set. | A206 | 15µ |
Avon | Burette Blood set (OBSOLETE). | A12 | 200µ |
Avon | Amberset Burette solution set. | A2000 | 15µ |
Avon | Amberset solution set. | A260 | 15µ |
Baxter
Table 4: Baxter non-dedicated sets.
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Baxter | Solution set. | C9615 | 15µ |
Baxter | Solution set. | C9614 | 15µ |
Baxter | Solution set. | C9604 | 15µ |
Baxter | Solution set. | C9606 | 15µ |
Baxter | Blood set. | C9609 | 200µ |
Baxter | Blood set. | C9612 | 200µ |
Baxter | Solution set. | C0337 | 15µ |
Baxter | Solution set. | C0334 | 15µ |
Baxter | Blood set. | C2071 | 200µ |
Baxter | Blood set. | C2159 | 200µ |
Baxter | Solution set. | C0360 | 15µ |
Baxter | Solution set. | C0361 | 15µ |
Baxter | Primary Solution set. | C0124 | 15µ |
Baxter | Solution set. | C0117 | 15µ |
Baxter | Solution set. | C0108 | 15µ |
Baxter | Solution set. | C0164 | 15µ |
Baxter | Burette Solution set. | C0163 | 15µ |
Baxter | Blood set. | C2579 | 170µ |
Baxter | Burette Blood set. | C0142 | 160µ |
Codan
Table 5: Codan non-dedicated sets.
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Codan | Infusion set. | 37.3138 | 15µ |
Codan | Blood set. | 45.5534 | 200µ |
Codan | Blood Burette set. | 45.5560 | 200µ |
Codan | Solution Burette set. | 59.3310 | 15µ |
Fresenius
Table 6: Fresenius non-dedicated sets.
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Fresenius | Simple solution set (recently withdrawn from market - will be reintroduced soon). | - | 15µ |
Fresenius | Metriset 120 ml burette set. | 23-05-941 | No filter (this set may be replaced soon with a 150 ml burette including a 15µ filter). |
Universal Hospital Supplies
Table 7: Universal non-dedicated sets.
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Universal | Mediflex - solution set | UN 998606 | 15µ |
Universal | Multiset - multi purpose blood, plasma or solution set | UN 998665 | 200µ |
Dedicated sets
Graseby
The Graseby pumps were developed originally with 3M, who still have their trademark imprinted on the sets, although the business is now wholly run/owned by Graseby. Graseby Medical Limited became SIMS Graseby Limited on 01.01.98.
Sets will ultimately become known by a revised pack code, (shown in the table below). This reflects the change of manufacturer from 3M to SIMS Graseby. Sets with this classification are expected to be introduced to the UK market in late 1998.
Table 8: Graseby Infusion Sets
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Graseby | Filter set (for solutions) | 8C-825 (also 3MD-825) | 15µ |
Graseby | Filter set (for solutions) | 8C4240 | 0.22µ |
Graseby | Blood set | 8C195 | 150µ |
Graseby | Opaque solution set | 1820.001 | No filter |
Graseby | Opaque solution set | 1820.002 | No filter |
Graseby | Lower adsorption solution set | 8C290 | No filter |
Graseby | Primary solution set | 820 | No filter |
Graseby | Primary solution set | 8C820 | No filter |
Graseby | Primary solution set | 8C860 | No filter |
Graseby | Primary solution set | 8C230 | No filter |
Graseby | Burette solution set | 8C1230 | No filter |
Graseby | Burette solution set | 8C1630 | No filter |
Graseby | Primary piggybacking solution set | 8C4220 | No filter |
Fresenius
Table 9: Fresenius Sets
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
Fresenius | Admin set for Verifuse portable pump. | V021007 | No filter |
Fresenius | Admin set for Verifuse portable pump - vented/non-vented. | V021011 | No filter |
Fresenius | Admin set for Verifuse portable pump. | V021014 | 1.2µ |
Fresenius | Admin set for Verifuse portable pump. | V021015 | 0.22µ |
Fresenius | Admin set for Inca pump. | 9004121 | 15µ |
Fresenius | Admin set for Inca pump (PVC free). | 9002111 | 15µ |
Fresenius | Admin set for Inca pump (lower Y site). | 9001611 | 15µ |
Fresenius | Rate Minder standard infusion set. | 9915071 | No filter |
Fresenius | Rate Minder infusion set with 0.22µ filter. | 9915081 | 0.22µ |
Fresenius | Rate Minder nitroglycerin infusion set. | 9916031 | No filter |
Imed
IVAC products are now marketed by Alaris medical systems.
Table 10: Imed sets
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
IMED | Primary set for use with Gemini series pumps. | 2210 | No filter |
IMED | Primary set for use with Gemini series pumps. | 2214 | 15µ |
IMED | ADD-I-MED set for use with Gemini series pumps. | 2220 | No filter |
IMED | Burette set for use with Gemini series pumps. | 2241 | No filter |
IMED | Nitro set for use with Gemini series pumps. | 2260 | No filter |
IMED | Blood set for use with Gemini series pumps. | 2277 | 150 µ |
IVAC
IVAC products are now marketed by Alaris medical systems. Extension sets (such as the G40020 etc) have been excluded as these products do not normally include filters
Table 11: IVAC sets
Manufacturer | Set Description | Cat No | Filter Info |
---|---|---|---|
IVAC | Solution set for 560 series pump. | G52703 | No filter. |
IVAC | Solution set for 560 series pump. | G52303 | 15µ |
IVAC | Solution set for 560 series pump. | G52503 | 15µ |
IVAC | Solution set for 560 series pump. | G50219 | 1.2µ |
IVAC | Solution set for 560 series pump. | G52033 | 0.22µ |
IVAC | Burette Solution set for 560 series pump. | 52103 | No filter |
IVAC | Blood set for 560 series pump. | 52080 | 200µ |
IVAC | Opaque set for 560 series pump. | G52543 | 15µ |
IVAC | PET Nitro set for 560 series pump. | G52053 | No filter |
IVAC | TPN set for 560 series pump. | C50019B | No filter |
IVAC | Burette Solution set for 560 series pump. | C50108B | 0.22µ |
IVAC | Solution set for 590 series pump. | G59793 | No Filter |
IVAC | Solution set for 590 series pump. | G59593 | 15µ |
IVAC | Solution set for 590 series pump. | G59693 | 15µ |
IVAC | Solution set for 590 series pump. | C59123 | 1.2µ |
IVAC | Burette set for 590 series pump. | 59103 | No filter |
IVAC | Blood set for 590 series pump. | 59980 | 200µ |
IVAC | Opaque set for 590 series pump. | 59643 | 15µ |
IVAC | PET Nitro set for 590 series pump. | 59953 | No filter |
IVAC | TPN set for 590 series pump. | C59903 | 15µ |
IVAC | Solution set for Signature edition pumps. | 72303 | 15µ |
IVAC | Solution set for Signature edition pumps. | 72503 | 15µ |
IVAC | Solution set for Signature edition pumps. | 72703 | No filter |
IVAC | Burette set for Signature edition pumps. | 72103 | No filter |
IVAC | Blood set for Signature edition pumps. | 72980 | 200µ |
IVAC | PET Nitro set for Signature edition pumps. | 72953 | No filter |
IVAC | Opaque set for Signature edition pumps. | 72543 | 15µ |
IVAC | IV cassette for 922/7/8 & 960 series pumps. | 9200 | No filter |
IVAC | IV cassette for 922/7/8 & 960 series pumps. | 9230 | No filter |
IVAC | IV cassette for 922/7/8 & 960 series pumps. | 9212 | 15µ |
IVAC | Microset with microbore tubing for 922/7/8 & 960 series pumps. | 9260 | No filter |
IVAC | Microset burette for 922/7/8 & 960 series pumps. | 9274 | No filter |
IVAC | IV cassette for 922/7/8 & 960 series pumps. | 9216 | 0.2µ |
IVAC | IV cassette (nitro set) for 922/7/8 & 960 series pumps. | 9630 | No filter |
IVAC | Unvented administration set for 280/580 pumps. | S75313 (was S75320) | No filter |
IVAC | Nitro set for 280/580 pumps. | S75053 | No filter |
IVAC | Standard administration set for 280/580 pumps. | S75853 | No filter |
IVAC | Secondary set for 280/580 pumps. | S75213 | No filter |
IVAC | Administration set for 280/580 pumps. | S75103 (was S75100) | No filter |